Description

2-Bromo-4-Ethoxy-1-Fluorobenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and incorporation into complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of active pharmaceutical ingredients (APIs), particularly in molecules requiring a fluorinated and brominated aromatic core for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine atoms contribute to efficacy and environmental persistence profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis, such as cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers or functional units for advanced polymers, liquid crystals, or organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Bromo-4-Ethoxy-1-Fluorobenzene
CAS No.	1555379-66-2
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	1-Bromo-3-Ethoxy-4-Fluorobenzene; 4-Ethoxy-2-Bromofluorobenzene; 2-Bromo-4-ethoxyfluorobenzene; 3-Ethoxy-4-fluorobromobenzene; Benzene, 2-bromo-4-ethoxy-1-fluoro-; 4-Fluoro-3-ethoxybromobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Ethoxy-1-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-8°C for long-term stability. The compound is light-sensitive and should be handled under appropriate conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.