Description

3-Ethoxy-2,6-Difluorobenzenesulfonylchloride is a high-purity, specialized organic intermediate of significant importance in modern synthetic chemistry. Its core value lies in its role as a key sulfonylation reagent, enabling the introduction of the sulfonyl functional group into target molecules with high selectivity. This compound is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Critical building block for synthesizing sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the difluoroethoxy moiety contributes to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating specialized polymers and functional materials with tailored surface properties.
• Chemical Biology Probes: Employed in the development of activity-based probes and labeling reagents for studying protein function.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	3-Ethoxy-2,6-Difluorobenzenesulfonylchloride
CAS No.	1552934-62-9
Molecular Formula	C8H7ClF2O3S
Molecular Weight	256.66 g/mol
Synonyms	2,6-Difluoro-3-ethoxybenzenesulfonyl chloride; 1-Ethoxy-2,6-difluoro-3-sulfonylchloridebenzene; Benzenesulfonyl chloride, 3-ethoxy-2,6-difluoro-; 3-Ethoxy-2,6-difluorophenylsulfonyl chloride; 2,6-Difluoro-3-ethoxyphenylsulfonyl chloride; DFES-Cl; EDFBS-Cl
EINECS	Contact for details

Quality Control

Every batch of 3-Ethoxy-2,6-Difluorobenzenesulfonylchloride is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.