Description

4-Bromo-2-(Propan-2-Yl)Benzene-1-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the sulfonamide functional group, which is pivotal for modulating the biological activity and physicochemical properties of target molecules. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including protease inhibitors, kinase inhibitors, and antibacterial agents.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides where the sulfonamide moiety enhances efficacy and selectivity.
• Material Science Research: Employed in the creation of specialty polymers, dyes, and functional organic materials that require sulfonamide linkages.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of activity-based probes targeting specific enzymes.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom organic synthesis projects and scale-up production for clinical trial materials.

Basic Information

Product Name	4-Bromo-2-(Propan-2-Yl)Benzene-1-Sulfonyl Chloride
CAS No.	1548128-18-2
Molecular Formula	C9H10BrClO2S
Molecular Weight	297.60 g/mol
Synonyms	4-Bromo-2-isopropylbenzenesulfonyl chloride; 2-Isopropyl-4-bromobenzenesulfonyl chloride; 1-Bromo-4-(chlorosulfonyl)-3-isopropylbenzene; p-Bromo-o-isopropylbenzenesulfonyl chloride; 1548128-18-2; 4-Bromo-2-(1-methylethyl)benzenesulfonyl chloride; 2-(Propan-2-yl)-4-bromobenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-(Propan-2-Yl)Benzene-1-Sulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We are committed to meeting the exacting standards required for pharmaceutical R&D and other high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; therefore, it must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent decomposition. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.