Description

(6-Trifluoromethyl-Imidazo[1,2-A]Pyridin-2-Yl)-Methanol is a high-value heterocyclic building block featuring a fused imidazopyridine core with a trifluoromethyl group and a hydroxymethyl substituent. This compound matters for its unique structural motifs, which are critical for modulating the physicochemical and pharmacokinetic properties of advanced molecules in drug discovery. Pharmaceutical and agrochemical R&D teams need this intermediate to synthesize novel active ingredients targeting a range of therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new chemical entities, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a specialized monomer or ligand in the development of advanced organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up campaigns in fine chemical production.

Basic Information

Product Name	(6-Trifluoromethyl-Imidazo[1,2-A]Pyridin-2-Yl)-Methanol
CAS No.	1514128-89-2
Molecular Formula	C9H7F3N2O
Molecular Weight	216.16 g/mol
Synonyms	2-(Hydroxymethyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine; (6-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)methanol; 6-Trifluoromethyl-2-imidazo[1,2-a]pyridinemethanol; Imidazo[1,2-a]pyridine-2-methanol, 6-(trifluoromethyl)-; 1514128-89-2
EINECS	Contact for details

Quality Control

Our (6-Trifluoromethyl-Imidazo[1,2-A]Pyridin-2-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.