Description

3-Pyridinemethanamine, 2,6-Difluoro- is a high-purity, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which combines a reactive primary amine with fluorine substituents at strategic positions, enabling precise modifications for developing novel compounds. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the fluoropyridine moiety enhances biological activity and metabolic stability.
• Ligand Synthesis: Employed in constructing complex ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Serves as a monomer or functionalizing agent for advanced polymers and electronic materials.
• Chemical Biology: Utilized as a probe or linker in bioconjugation and the development of biochemical tools.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes.

Basic Information

Product Name	3-Pyridinemethanamine, 2,6-Difluoro-
CAS No.	1511582-33-4
Molecular Formula	C6H6F2N2
Molecular Weight	144.12 g/mol
Synonyms	(2,6-Difluoropyridin-3-yl)methanamine; 2,6-Difluoro-3-pyridinemethanamine; 3-(Aminomethyl)-2,6-difluoropyridine; 2,6-Difluoro-3-pyridylmethylamine; 2,6-Difluoropyridine-3-methanamine; 3-Aminomethyl-2,6-difluoropyridine
EINECS	Contact for details

Quality Control

Our 3-Pyridinemethanamine, 2,6-Difluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.