Description

2-Chloro-4-Fluoro-5-Methylbenzyl Bromide is a versatile and highly reactive halogenated benzyl bromide intermediate. This compound matters for its role as a critical building block in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced material precursors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry for introducing the benzyl moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where specific halogen substitution patterns are required for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine ligands or organometallic catalysts used in cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers or liquid crystals that incorporate halogenated aromatic units.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems due to its reactive benzyl bromide group.
• Custom Synthesis and Contract Manufacturing: A valuable intermediate for fine chemical suppliers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Chloro-4-Fluoro-5-Methylbenzyl Bromide
CAS No.	1510609-23-0
Molecular Formula	C8H7BrClF
Molecular Weight	237.50 g/mol
Synonyms	1-(Bromomethyl)-2-chloro-4-fluoro-5-methylbenzene; (2-Chloro-4-fluoro-5-methylphenyl)methyl bromide; 5-(Bromomethyl)-2-chloro-4-fluorotoluene; α-Bromo-2-chloro-4-fluoro-5-methyltoluene; 2-Chloro-4-fluoro-5-methylbenzylbromide; 2-Chloro-4-fluoro-5-methyl-benzylbromide; Benzene, 1-(bromomethyl)-2-chloro-4-fluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-5-Methylbenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.