Description

2-Methyl-2H-1,2,3-Triazole-4-Sulfonylchloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for introducing the sulfonamide functional group, enabling the creation of complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients, heterocyclic compounds, and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing sulfonamide moieties with potential biological activity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the triazole-sulfonamide structure confers specific modes of action.
• Material Science: Employed in the creation of specialty polymers, dyes, and functional materials that require the incorporation of sulfonamide linkages.
• Chemical Research: Serves as a valuable reagent in medicinal chemistry and process development for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands and organocatalysts containing triazole and sulfonamide functional groups.

Basic Information

Product Name	2-Methyl-2H-1,2,3-Triazole-4-Sulfonylchloride
CAS No.	1496511-49-9
Molecular Formula	C3H4ClN3O2S
Molecular Weight	181.60 g/mol
Synonyms	2-Methyl-1,2,3-triazole-4-sulfonyl chloride; 2-Methyl-2H-1,2,3-triazole-4-sulfonyl chloride; 4-(Chlorosulfonyl)-2-methyl-2H-1,2,3-triazole; 1,2,3-Triazole-4-sulfonyl chloride, 2-methyl-; 2-Methyl-1,2,3-triazole-4-sulphonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-2H-1,2,3-Triazole-4-Sulfonylchloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.