Description

Pki-179 (Hydrochloride) is a high-purity chemical compound used as a key intermediate in advanced pharmaceutical research and development. This compound is critical for synthesizing novel therapeutic agents, particularly in the fields of oncology and targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and contract research organizations (CROs) requiring reliable, high-quality building blocks for complex molecular synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Oncology Research: Used in the development of targeted cancer therapies and kinase inhibitors.
• Biochemical Screening: Serves as a reference standard or a probe compound in high-throughput screening (HTS) assays.
• Academic Research: Employed in university and institutional labs for medicinal chemistry and pharmacology studies.
• Preclinical Development: Integral to the drug discovery pipeline for producing compounds for in vitro and in vivo testing.

Basic Information

Product Name	Pki-179 (Hydrochloride)
CAS No.	1463510-35-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PKI-179 HCl; NVP-PKI179 hydrochloride; PKI 179 hydrochloride; 4-Amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one hydrochloride (IUPAC-based); UNII-7V8R1C4P4C; BDBM50190063; CHEMBL3186472
EINECS	Contact for details

Quality Control

Our Pki-179 (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.