Description

2-Bromo-5-Fluoro-3-Nitrotoluene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and nitro substituents on a toluene backbone, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of its halogen and nitro functional groups.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the creation of complex ligands for transition metal catalysis and organocatalysts due to its electron-withdrawing substituents.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized azo dyes and pigments where halogen atoms enhance lightfastness and color properties.

Basic Information

Product Name	2-Bromo-5-Fluoro-3-Nitrotoluene
CAS No.	1463053-91-9
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.03 g/mol
Synonyms	1-Bromo-4-fluoro-2-methyl-5-nitrobenzene; 2-Methyl-5-nitro-1-bromo-4-fluorobenzene; 5-Fluoro-2-bromo-3-nitrotoluene; Toluene, 2-bromo-5-fluoro-3-nitro-; 3-Nitro-2-bromo-5-fluorotoluene; 2-Bromo-5-fluoro-3-nitro-1-methylbenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Fluoro-3-Nitrotoluene is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.