Description

n-Ethyl-n-Methylsulfamoyl Fluoride is a specialized organofluorine compound belonging to the sulfamoyl fluoride class, serving as a key synthetic intermediate. Its primary value lies in its role as a versatile building block for introducing the sulfamoyl fluoride moiety into more complex molecular architectures, which is critical in modern medicinal and agrochemical research. This high-purity reagent is essential for R&D chemists and process development scientists working in pharmaceutical discovery, crop protection, and advanced material science.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel sulfonamide-based active pharmaceutical ingredients (APIs) and protease inhibitors.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that incorporate sulfamoyl functional groups for enhanced efficacy.
• Chemical Biology Probe Development: Serves as a reactive handle for creating activity-based probes (ABPs) to study enzyme function and mechanism, particularly for sulfatases and related enzymes.
• Material Science Research: Employed in the synthesis of specialty polymers and functional materials where the sulfamoyl fluoride group can impart specific chemical or physical properties.
• Cross-Coupling & Functionalization: Acts as an electrophilic reagent for the selective introduction of fluorine and sulfonamide groups into complex organic molecules under controlled conditions.

Basic Information

Product Name	n-Ethyl-n-Methylsulfamoyl Fluoride
CAS No.	1458771-72-6
Molecular Formula	C₃H₈FNO₂S
Molecular Weight	141.16 g/mol
Synonyms	N-Ethyl-N-methylsulfamoyl fluoride; Ethyl(methyl)sulfamoyl fluoride; Sulfamoyl fluoride, N-ethyl-N-methyl-; N-Ethyl-N-methylsulfamoyl fluoride; 1458771-72-6; SCHEMBL24268231; DTXSID70731819
EINECS	Contact for details

Quality Control

Every batch of n-Ethyl-n-Methylsulfamoyl Fluoride is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical techniques including NMR, HPLC, and GC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.