Description

β-Catenin-In-2 is a potent and selective small molecule inhibitor of the β-catenin signaling pathway, a critical regulator of cell growth and proliferation. This compound is essential for researchers and pharmaceutical developers targeting oncogenic pathways, particularly in cancers driven by Wnt/β-catenin dysregulation. It is a vital tool for high-throughput screening, target validation, and preclinical drug discovery programs in academic, biotechnology, and pharmaceutical R&D sectors.

Application

• Oncology Research: Used as a key pharmacological tool to study the role of β-catenin in various cancers, including colorectal, hepatocellular, and breast cancer.
• Drug Discovery & Development: Serves as a lead compound or reference standard for developing novel anti-cancer therapeutics targeting the Wnt signaling pathway.
• High-Throughput Screening (HTS): Employed in cell-based and biochemical assays to identify and validate new inhibitors of β-catenin-mediated transcription.
• Mechanistic Studies: Facilitates research into stem cell biology, tissue regeneration, and developmental processes governed by Wnt/β-catenin signaling.
• Biomarker Research: Aids in understanding the correlation between β-catenin activity and disease progression or treatment response.

Basic Information

Product Name	β-Catenin-In-2
CAS No.	1458664-10-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	β-Catenin-In-2; β-Catenin Inhibitor 2; Wnt/β-catenin pathway inhibitor; CAS 1458664-10-2; B-Catenin-In-2; BCATIN2; β-Catenin Signaling Inhibitor
EINECS	Contact for details

Quality Control

Our β-Catenin-In-2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.