Description

Sh-4-54 CAS NO 1456632-40-8 is a high-purity, small-molecule chemical compound designed for advanced research and development applications. This product is valued for its role as a potent and selective inhibitor in biochemical and pharmacological studies, enabling critical pathway analysis and target validation. It is primarily sought by research institutions, pharmaceutical developers, and biotechnology companies engaged in drug discovery and life science research.

Application

• Biochemical Research: Used as a selective kinase inhibitor to study specific cellular signaling pathways and protein functions.
• Pharmaceutical R&D: Serves as a key reference standard or active pharmaceutical ingredient (API) intermediate in early-stage drug discovery programs.
• Target Validation: Employed in vitro and in vivo to validate novel therapeutic targets for oncology, neurology, and other disease areas.
• High-Throughput Screening (HTS): Utilized as a control compound in assay development and screening campaigns to identify new drug candidates.
• Academic Research: Supports fundamental biological research in universities and institutes, investigating mechanisms of disease.
• Proteomics & Chemical Biology: Acts as a chemical probe to map protein interactions and understand complex biological networks.

Basic Information

Product Name	Sh-4-54
CAS No.	1456632-40-8
Molecular Formula	C₂₀H₂₀N₆O₂
Molecular Weight	376.41 g/mol
Synonyms	SH-4-54; SH454; 2-Pyridinecarboxamide, N-[4-[[(3S)-3-(1H-indol-3-ylmethyl)-2,5-dioxo-1-pyrrolidinyl]methyl]phenyl]-; STAT3 Inhibitor SH-4-54; SH 4-54; N-[4-[[(3S)-3-(1H-indol-3-ylmethyl)-2,5-dioxo-1-pyrrolidinyl]methyl]phenyl]-2-pyridinecarboxamide; SH4-54; SH4 54
EINECS	Contact for details

Quality Control

Every batch of Sh-4-54 is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. Keep the container tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.