Description

S3I-1757 is a high-purity, small molecule compound identified by CAS NO 1456602-51-9, primarily utilized as a potent and selective research-grade chemical probe. This compound is valued for its specific inhibitory activity in biochemical and cellular research pathways, enabling precise scientific investigation. It is essential for pharmaceutical R&D, academic research institutions, and biotechnology companies focused on target validation and early-stage drug discovery.

Application

• Biochemical Research: Used as a selective inhibitor in enzymatic assays to study specific protein functions and signaling cascades.
• Cellular Biology: Employed in cell-based studies to investigate the role of target proteins in proliferation, apoptosis, and other cellular processes.
• Pharmaceutical R&D: Serves as a critical tool compound for target validation and as a starting point for medicinal chemistry programs in drug discovery.
• Academic Research: Facilitates fundamental biological research in universities and institutes, helping to elucidate disease mechanisms.
• High-Throughput Screening (HTS): Can be used as a reference or control compound in screening campaigns to identify novel drug candidates.

Basic Information

Product Name	S3I-1757
CAS No.	1456602-51-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	S3I1757; S3I 1757; 2-[(2,4-Dichlorophenyl)methyl]-4-(4-methoxyphenyl)-1,2,4-triazolidine-3,5-dione (IUPAC-based); STAT3 Inhibitor S3I-1757; STAT3 Signaling Inhibitor
EINECS	Contact for details

Quality Control

Our S3I-1757 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to meet exacting standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.