Description

Sah-Ezh2 CAS NO 1453222-26-8 is a high-purity, small-molecule chemical compound with significant utility in advanced research and development. This compound is valued for its role as a potent and selective inhibitor, enabling critical studies in epigenetics and cellular signaling pathways. It is primarily sought after by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in drug discovery and molecular biology. Our supply ensures consistent quality and reliable availability for your most demanding projects.

Application

• Biomedical Research: Used as a selective inhibitor of EZH2 (Enhancer of Zeste Homolog 2) for studying histone methylation and epigenetic regulation.
• Oncology Drug Discovery: A key tool compound in the development of targeted cancer therapies, particularly for lymphomas and other malignancies driven by EZH2 dysregulation.
• Cellular Pathway Analysis: Facilitates the investigation of Polycomb Repressive Complex 2 (PRC2) function and its impact on gene expression and cell differentiation.
• Biochemical Assay Development: Serves as a reference standard and active component in high-throughput screening (HTS) and enzymatic assays.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate the efficacy and mechanism of action of epigenetic modulators.

Basic Information

Product Name	Sah-Ezh2
CAS No.	1453222-26-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sah-Ezh2; SAH-EZH2; EZH2 Inhibitor SAH-EZH2; UNC1999 analog; (S)-Pyridone-based EZH2 inhibitor; Enhancer of Zeste Homolog 2 Inhibitor; PRC2 Inhibitor; Epigenetic inhibitor 1453222-26-8
EINECS	Contact for details

Quality Control

Our Sah-Ezh2 is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and potency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting full compliance with our rigorous specifications. We support research and development with material traceability and reliable batch-to-batch reproducibility.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.