Description

2-Fluoro-3-Carboxypyridine-5-Boronic Acid is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound matters because it combines a reactive boronic acid group with a carboxylic acid and a fluorine substituent on a pyridine scaffold, enabling precise cross-coupling and derivatization reactions. It is primarily needed by pharmaceutical, agrochemical, and advanced materials researchers for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and sensors.
• Chemical Biology Probes: Facilitates the creation of fluorescent tags and molecular probes for biological imaging and diagnostics.
• Custom Synthesis & Contract Manufacturing: A critical building block for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Fluoro-3-Carboxypyridine-5-Boronic Acid
CAS No.	1451393-51-3
Molecular Formula	C7H5BFNO4
Molecular Weight	184.93 g/mol
Synonyms	5-Borono-2-fluoro-3-pyridinecarboxylic acid; (5-Carboxy-6-fluoropyridin-3-yl)boronic acid; 2-Fluoro-5-borono-3-pyridinecarboxylic acid; 3-Carboxy-6-fluoro-5-pyridineboronic acid; 6-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinic acid (pinacol ester precursor); 2-Fluoro-3-carboxy-5-pyridinylboronic acid; 2-Fluoro-3-pyridinecarboxylic acid-5-boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Carboxypyridine-5-Boronic Acid is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.