Description

2-Fluoro-3-Methoxypyridine-5-Boronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates containing fluorinated pyridine scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated heterocyclic structures.
• Material Science: Serves as a building block for creating novel organic electronic materials, ligands for catalysts, and liquid crystals.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a versatile boronic acid coupling partner to introduce the 2-fluoro-3-methoxypyridine moiety into more complex molecular architectures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic pathways and novel compound libraries.
• Ligand Synthesis: Can be utilized to create specialized bidentate or tridentate ligands for transition metal catalysis.

Basic Information

Product Name	2-Fluoro-3-Methoxypyridine-5-Boronic Acid
CAS No.	1451392-07-6
Molecular Formula	C6H7BFNO3
Molecular Weight	170.94 g/mol
Synonyms	(2-Fluoro-3-methoxypyridin-5-yl)boronic acid; 5-Borono-2-fluoro-3-methoxypyridine; 2-Fluoro-3-methoxy-5-pyridineboronic acid; 3-Methoxy-2-fluoropyridine-5-boronic acid; 2-Fluoro-3-methoxypyridine-5-borononic acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluoro-3-methoxypyridine (pinacol ester precursor)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methoxypyridine-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) and desiccated for long-term storage to maintain optimal purity and reactivity. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical: ≥98.5%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.