Description

Methyl 2-(5-Fluoropyridin-2-Yl)Acetate CAS NO 1449599-07-8 is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the 5-fluoropyridin-2-yl moiety into complex molecular architectures, enabling the development of novel compounds with targeted properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluoropyridine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers where fluorinated aromatic systems are required.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis projects and scale-up activities in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	Methyl 2-(5-Fluoropyridin-2-Yl)Acetate
CAS No.	1449599-07-8
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	Methyl (5-Fluoropyridin-2-yl)acetate; 2-(5-Fluoropyridin-2-yl)acetic acid methyl ester; (5-Fluoro-2-pyridinyl)acetic acid methyl ester; Methyl 2-(5-fluoro-2-pyridinyl)acetate; 1449599-07-8; Acetic acid, 2-(5-fluoro-2-pyridinyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(5-Fluoropyridin-2-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.