Description

2-Bromo-4-(Trifluoromethoxy)Biphenyl is a high-value, multi-functional aromatic compound featuring both bromine and trifluoromethoxy substituents. This unique structure makes it a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used as a building block for developing new-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Acts as a core component in the production of advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Functional Material Research: Employed in academic and industrial research for creating novel polymers and organic semiconductors with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up production.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethoxy)Biphenyl
CAS No.	1449008-27-8
Molecular Formula	C13H8BrF3O
Molecular Weight	317.11 g/mol
Synonyms	2-Bromo-4'-(trifluoromethoxy)-1,1'-biphenyl; [1,1'-Biphenyl]-2-bromo-4-(trifluoromethoxy); 4'-Trifluoromethoxy-2-bromobiphenyl; 2-Bromo-4-trifluoromethoxybiphenyl; 2-Bromobiphenyl-4-yl trifluoromethyl ether
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(Trifluoromethoxy)Biphenyl is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our products are suitable for demanding applications in regulated industries. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.