Description

1-(2-Fluoro-5-Methylpyridin-3-Yl)Ethan-1-Ol is a high-purity fluorinated pyridine derivative, serving as a crucial chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine atom and the hydroxyl group, enabling precise molecular construction for complex target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides where the fluoropyridine moiety enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate in the synthesis of functionalized organic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	1-(2-Fluoro-5-Methylpyridin-3-Yl)Ethan-1-Ol
CAS No.	1449008-18-7
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	1-(2-Fluoro-5-methylpyridin-3-yl)ethanol; 3-(1-Hydroxyethyl)-2-fluoro-5-methylpyridine; 2-Fluoro-5-methyl-3-(1-hydroxyethyl)pyridine; α-Methyl-2-fluoro-5-methyl-3-pyridinemethanol; (2-Fluoro-5-methyl-3-pyridinyl)ethanol; 1-(2-Fluoro-5-methyl-3-pyridinyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-5-Methylpyridin-3-Yl)Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.