Description

3-Bromo-4-Methyl-2-(Trifluoromethyl)Pyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and trifluoromethyl substituents, makes it an indispensable intermediate for introducing specific functionalities into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing complex ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Bromo-4-Methyl-2-(Trifluoromethyl)Pyridine
CAS No.	1448776-80-4
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	2-(Trifluoromethyl)-3-bromo-4-methylpyridine; 3-Bromo-4-methyl-2-trifluoromethylpyridine; 4-Methyl-3-bromo-2-(trifluoromethyl)pyridine; Pyridine, 3-bromo-4-methyl-2-(trifluoromethyl)-; 1448776-80-4
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Methyl-2-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.