Description

2-Fluoro-5-(Trifluoromethoxy)Benzenesulfonylchloride is a high-value, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride group and unique fluorine-substituted aromatic ring, enabling the precise introduction of complex sulfonamide and sulfonate functionalities. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of protease inhibitors, herbicides, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing advanced herbicides and pesticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the creation of specialty polymers and advanced materials with specific surface properties.
• Chemical Research: A versatile reagent for introducing the 2-fluoro-5-(trifluoromethoxy)phenylsulfonyl moiety in medicinal chemistry and discovery programs.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalytic systems.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethoxy)Benzenesulfonylchloride
CAS No.	1446478-70-1
Molecular Formula	C7H3ClF4O3S
Molecular Weight	278.61 g/mol
Synonyms	2-Fluoro-5-(trifluoromethoxy)benzenesulfonyl chloride; 1-Fluoro-4-(trifluoromethoxy)benzene-2-sulfonyl chloride; 2-Fluoro-α,α,α-trifluoro-p-anisolesulfonyl chloride; 5-(Trifluoromethoxy)-2-fluorobenzenesulfonyl chloride; Benzenesulfonyl chloride, 2-fluoro-5-(trifluoromethoxy)-; 2-Fluoro-5-trifluoromethoxy-benzenesulfonylchloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Trifluoromethoxy)Benzenesulfonylchloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically meeting standards for research and development use. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality commitment supports your critical synthesis work with reliable material performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.