Description

Methyl 6-Amino-2-Fluoropyridine-3-Carboxylate CAS NO 1445962-42-4 is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a fluorine substituent, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the design of novel chelating ligands and organocatalysts for asymmetric synthesis and metal-catalyzed reactions.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes to study biological processes.

Basic Information

Product Name	Methyl 6-Amino-2-Fluoropyridine-3-Carboxylate
CAS No.	1445962-42-4
Molecular Formula	C7H7FN2O2
Molecular Weight	170.14 g/mol
Synonyms	Methyl 6-Amino-2-Fluoro-3-pyridinecarboxylate; 2-Fluoro-6-aminonicotinic Acid Methyl Ester; 6-Amino-2-fluoropyridine-3-carboxylic Acid Methyl Ester; Methyl 2-Fluoro-6-aminonicotinate; 3-Pyridinecarboxylic acid, 6-amino-2-fluoro-, methyl ester; Methyl 6-Amino-2-Fluoronicotinate; 1445962-42-4
EINECS	Contact for details

Quality Control

Our Methyl 6-Amino-2-Fluoropyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.