Description

1-[(2-Fluorophenyl)Methyl]Cyclopropan-1-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct cyclopropane amine structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those targeting neurological disorders.
• API Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its fluorinated aromatic and strained cyclopropane ring system.
• Preclinical Development: Supplied for the synthesis of compounds required for pharmacological profiling, toxicology studies, and early-stage development.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1-[(2-Fluorophenyl)Methyl]Cyclopropan-1-Amine Hydrochloride
CAS No.	1439897-84-3
Molecular Formula	C11H13ClFN
Molecular Weight	213.68 g/mol
Synonyms	1-[(2-Fluorobenzyl)]cyclopropanamine hydrochloride; 1-(2-Fluorobenzyl)cyclopropan-1-amine HCl; 1-(2-Fluorobenzyl)cyclopropanamine hydrochloride; α-(2-Fluorophenyl)-α-cyclopropylmethylamine hydrochloride; (1-(2-Fluorobenzyl)cyclopropyl)amine hydrochloride; 2-Fluoro-α-(cyclopropylaminomethyl)benzene hydrochloride; 1-(2-Fluorophenylmethyl)cyclopropanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[(2-Fluorophenyl)Methyl]Cyclopropan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.