Description

4-Ethoxy-2,6-Difluorobenzenesulfonyl Chloride is a high-purity, specialized sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile electrophilic reagent for introducing the sulfonamide functional group, which is pivotal in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to create novel sulfonamide-based molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-containing drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides that utilize the sulfonamide moiety for enhanced biological activity.
• Chemical Research & Development: A valuable reagent for constructing complex molecular architectures in academic and industrial R&D settings.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialized polymers with unique properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Item	Details
Product Name	4-Ethoxy-2,6-Difluorobenzenesulfonyl Chloride
CAS No.	1432129-18-4
Molecular Formula	C8H7ClF2O3S
Molecular Weight	256.65 g/mol
Synonyms	2,6-Difluoro-4-ethoxybenzenesulfonyl chloride; 1-Ethoxy-3,5-difluoro-4-sulfonylchloridobenzene; 4-Ethoxy-2,6-difluorobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 4-ethoxy-2,6-difluoro-; 1432129-18-4
EINECS	Contact for details

Quality Control

Every batch of 4-Ethoxy-2,6-Difluorobenzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and GC, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.