Description

Lorcaserin Hydrochloride CAS NO 1431697-94-7 is a selective serotonin 2C receptor agonist used as an active pharmaceutical ingredient (API). This compound is critical for the development and manufacture of prescription weight management medications. It is primarily required by pharmaceutical companies, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in metabolic disorder therapeutics.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of prescription anti-obesity drugs.
• Reference Standard: Serves as a high-purity standard for analytical method development and validation in quality control laboratories.
• Clinical Research: Utilized in preclinical and clinical studies investigating new treatments for obesity and related metabolic syndromes.
• Drug Development: A key intermediate or final compound in the R&D pipeline for novel central nervous system (CNS) targeting therapies.
• Generic Drug Manufacturing: Essential for companies producing generic versions of weight management medications following patent expiration.

Basic Information

Product Name	Lorcaserin Hydrochloride
CAS No.	1431697-94-7
Molecular Formula	C11H15ClN2O•HCl
Molecular Weight	241.12 g/mol (free base) / 277.59 g/mol (hydrochloride salt)
Synonyms	Lorcaserin HCl; APD356; (1R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride; Belviq (Brand Name); BVT-933; (R)-Lorcaserin Hydrochloride
EINECS	Contact for details

Quality Control

Our Lorcaserin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and residual solvent analysis to ensure compliance with ICH guidelines and pharmaceutical-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Total Impurities (HPLC)	≤ 1.0%
Any Single Unknown Impurity	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.