Description

2-(2,3,4-Trifluorophenyl)Pyridine is a high-value fluorinated pyridine derivative, a key building block in modern organic synthesis. This compound is essential for the development of advanced materials and active pharmaceutical ingredients (APIs), where its unique trifluorophenyl-pyridine scaffold imparts desirable physicochemical properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced bioactivity and stability.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms contribute to improved lipophilicity and metabolic stability.
• Ligand for Catalysis: Serves as a sophisticated ligand precursor in transition metal catalysis for cross-coupling and other complex organic transformations.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and liquid crystals.
• Fluorine Chemistry Studies: A valuable substrate for academic and industrial research into the effects of polyfluorination on aromatic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specialized fluorinated heterocycle.

Basic Information

Product Name	2-(2,3,4-Trifluorophenyl)Pyridine
CAS No.	1431374-74-1
Molecular Formula	C11H6F3N
Molecular Weight	209.17 g/mol
Synonyms	2-(2,3,4-Trifluorophenyl)pyridine; Pyridine, 2-(2,3,4-trifluorophenyl)-; 2,3,4-Trifluoro-2-pyridinylbenzene; (2,3,4-Trifluorophenyl)pyridine; 2-Pyridyl-2,3,4-trifluorobenzene; 1431374-74-1; 2-(2,3,4-Trifluorophenyl)Pyridine CAS NO 1431374-74-1
EINECS	Contact for details

Quality Control

Our 2-(2,3,4-Trifluorophenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.