Description

Gsk-Lsd1 CAS NO 1431368-48-7 is a potent and selective lysine-specific demethylase 1 (LSD1) inhibitor, a key compound in epigenetic research and therapeutic development. It matters as a critical tool for investigating gene expression regulation, cell differentiation, and the role of histone methylation in disease pathways. This product is essential for pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, neurology, and other therapeutic areas where epigenetic modulation is a target.

Application

• Biochemical Research: Used as a reference standard and active compound in studies of histone demethylation mechanisms and epigenetic regulation.
• Pharmaceutical Development: Serves as a lead compound or pharmacological tool in the discovery and validation of novel LSD1-targeted therapies.
• Oncology Research: Investigated for its potential to inhibit cancer cell proliferation, induce differentiation, and overcome drug resistance in various cancer models.
• Neuroscientific Studies: Applied in research exploring the role of LSD1 in neurological disorders, neural development, and synaptic plasticity.
• Stem Cell Research: Utilized to modulate the epigenetic state and influence the differentiation potential of pluripotent stem cells.
• In Vitro & In Vivo Assays: Functions as a key reagent in high-throughput screening (HTS) and preclinical efficacy studies to evaluate LSD1 inhibition.

Basic Information

Product Name	Gsk-Lsd1
CAS No.	1431368-48-7
Molecular Formula	C24H27FN4O2
Molecular Weight	422.50 g/mol
Synonyms	GSK-LSD1; GSK2879552; (R)-N1-((6,7-Dihydro-5H-pyrrolo[1,2-c]imidazol-1-yl)methyl)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)oxalamide; (R)-N-((6,7-Dihydro-5H-pyrrolo[1,2-c]imidazol-1-yl)methyl)-N'-(1-(5-fluoropyrimidin-2-yl)ethyl)oxalamide; LSD1 Inhibitor GSK2879552; GSK-2879552
EINECS	Contact for details

Quality Control

Our Gsk-Lsd1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and structural confirmation via MS and NMR. Certificates of Analysis (COA) detailing all specifications are provided to support your regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. Store in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.