Description

(5-Fluoro-3-Methylpyridin-2-Yl)Methanamine Hydrochloride is a high-purity, pharmaceutically relevant building block offered as a stable hydrochloride salt. This compound is a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and agrochemical industries seeking reliable, high-quality intermediates for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in CNS and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its fluorinated pyridine core.
• Chemical Research & Development: Serves as a versatile precursor for medicinal chemistry and process chemistry optimization studies.
• Ligand and Catalyst Development: The amine functionality makes it suitable for creating specialized ligands in catalytic systems.
• Custom Synthesis Starting Material: Provides a defined, high-purity starting point for contract research organizations (CROs) and CDMOs.

Basic Information

Product Name	(5-Fluoro-3-Methylpyridin-2-Yl)Methanamine Hydrochloride
CAS No.	1428532-86-8
Molecular Formula	C7H10ClFN2
Molecular Weight	176.62 g/mol
Synonyms	2-(Aminomethyl)-5-fluoro-3-methylpyridine hydrochloride; 1-(5-Fluoro-3-methylpyridin-2-yl)methanamine hydrochloride; (5-Fluoro-3-methyl-2-pyridinyl)methanamine hydrochloride; 2-Pyridinemethanamine, 5-fluoro-3-methyl-, hydrochloride; 5-Fluoro-3-methylpicolinamine hydrochloride
EINECS	Contact for details

Quality Control

Our (5-Fluoro-3-Methylpyridin-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.