Description

5-Cyclopropyl-2-Fluoro-4-Methylpyridine is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its unique structure, featuring a cyclopropyl and a fluorine substituent on the pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and cyclopropyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis, enabling more efficient and selective chemical transformations.
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals, where its aromatic core and substituents modify electronic and physical properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological processes and enzyme mechanisms due to its potential as a bioisostere.

Basic Information

Product Name	5-Cyclopropyl-2-Fluoro-4-Methylpyridine
CAS No.	1428234-77-8
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	2-Fluoro-4-methyl-5-cyclopropylpyridine; 5-Cyclopropyl-2-fluoro-4-picoline; 4-Methyl-5-cyclopropyl-2-fluoropyridine; 2-Fluoro-5-cyclopropyl-4-methylpyridine; 5-Cyclopropyl-2-fluoro-4-methylpyridine (IUPAC); 2-Fluoro-4-methyl-5-(cyclopropyl)pyridine; 4-Methyl-2-fluoro-5-cyclopropylpyridine
EINECS	Contact for details

Quality Control

We supply 5-Cyclopropyl-2-Fluoro-4-Methylpyridine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR are available upon request. We adhere to a strict quality management system to guarantee batch-to-batch consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Typical 98-99%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.