Description

(2-Bromo-4-Chlorophenyl)Methanesulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the (2-bromo-4-chlorophenyl)methanesulfonyl moiety into target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogenated phenyl group confers specific biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling (ABPP).
• Ligand & Catalyst Development: Employed in the creation of novel organocatalysts or metal-chelating ligands for asymmetric synthesis.

Basic Information

Item	Details
Product Name	(2-Bromo-4-Chlorophenyl)Methanesulfonyl Chloride
CAS No.	1427379-23-4
Molecular Formula	C7H5BrCl2O2S
Molecular Weight	304.0 g/mol
Synonyms	2-Bromo-4-chlorobenzylsulfonyl chloride; 1-(Bromomethyl)-2-chloro-4-bromobenzene sulfonyl chloride; (2-Bromo-4-chlorophenyl)methylsulfonyl chloride; α-Bromo-2-chloro-4-bromotoluene sulfonyl chloride; 2-Bromo-4-chloro-α-toluenesulfonyl chloride; BCBMSC; (2-Br-4-Cl-Ph)CH2SO2Cl
EINECS	Contact for details

Quality Control

Every batch of (2-Bromo-4-Chlorophenyl)Methanesulfonyl Chloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.