Description

4-(2-Fluoropropan-2-Yl)Pyrimidine-5-Carbonitrile is a high-value fluorinated pyrimidine derivative, a crucial building block in modern synthetic chemistry. Its unique structure, featuring both a nitrile and a fluorinated alkyl group, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(2-Fluoropropan-2-Yl)Pyrimidine-5-Carbonitrile
CAS No.	1427195-26-3
Molecular Formula	C8H8FN3
Molecular Weight	165.17 g/mol
Synonyms	5-Cyano-4-(2-fluoropropan-2-yl)pyrimidine; 4-(2-Fluoro-2-propanyl)-5-pyrimidinecarbonitrile; 4-(1-Fluoro-1-methylethyl)pyrimidine-5-carbonitrile; 2-Fluoro-2-(5-cyanopyrimidin-4-yl)propane; Pyrimidine-5-carbonitrile, 4-(2-fluoropropan-2-yl)-; 1427195-26-3
EINECS	Contact for details

Quality Control

Our production of 4-(2-Fluoropropan-2-Yl)Pyrimidine-5-Carbonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.