Description

Thailanstatin C CAS NO 1426953-24-3 is a potent, naturally occurring macrocyclic lactone compound of significant interest in advanced pharmaceutical research. This molecule matters for its role as a highly selective and potent cytotoxin, making it a valuable tool compound and a promising lead structure in oncology drug discovery. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on developing novel anti-cancer therapeutics and investigating mechanisms of cellular apoptosis.

Application

• Oncology Research & Drug Discovery: Serves as a critical lead compound and molecular probe for studying apoptosis pathways and developing novel anti-cancer agents.
• Biochemical & Pharmacological Studies: Used as a reference standard and active agent in in vitro and cellular assays to investigate cytotoxicity and mechanism of action.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in chemical biology and natural product pharmacology.
• Preclinical Development: Utilized in the early-stage development of targeted cancer therapies due to its specific biological activity.
• High-Throughput Screening (HTS): Acts as a control or benchmark compound in screening libraries to identify new drug candidates.

Basic Information

Product Name	Thailanstatin C
CAS No.	1426953-24-3
Molecular Formula	C34H48N2O10S
Molecular Weight	676.82 g/mol
Synonyms	Thailanstatin C; FR901464 analogue; Splicing inhibitor FR901464 derivative; (2S,3S,4R,5R,6R,8R,10S,11S,12S,14S,15R,17R,19S,20R,21S,22R,23S,24S,25R,26S)-26-Hydroxy-5,8,10,12,14,17,19,21,23,25-decamethyl-2,4,11,15,20,24-hexaoxo-7,18-dioxa-3,13,16,22-tetrazatetracyclo[19.3.1.16,9.113,18]hexacosa-1(25),6,9,13,15,21,23-heptaene-22-sulfonic acid
EINECS	Contact for details

Quality Control

Our Thailanstatin C is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, inert environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.