Description

Pde2/Pde10-In-1 CAS NO 1426833-08-0 is a high-purity, dual-target small molecule inhibitor designed for advanced pharmaceutical research and development. This compound is critical for investigating the complex interplay between phosphodiesterase 2 (PDE2) and phosphodiesterase 10 (PDE10) in neurological and psychiatric pathways. It is primarily utilized by research scientists and process chemists in the pharmaceutical and biotechnology sectors for target validation, lead optimization, and preclinical studies.

Application

• Neurological Disorder Research: A key tool compound for studying the role of PDE2 and PDE10 in conditions such as schizophrenia, Huntington's disease, and cognitive impairments.
• Psychiatric Drug Discovery: Used in high-throughput screening (HTS) and in vitro assays to identify and characterize novel therapeutic candidates targeting dual PDE inhibition.
• Biochemical Pathway Analysis: Enables detailed investigation of cyclic nucleotide signaling (cAMP/cGMP) in cellular models and brain tissue samples.
• Preclinical Development: Serves as a reference standard or pharmacodynamic marker in animal model studies for central nervous system (CNS) agents.
• Process Chemistry & API Development: Used as an intermediate or reference material in the synthesis and scale-up of potential active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Supports fundamental neuroscience research in universities and government research institutes worldwide.

Basic Information

Product Name	Pde2/Pde10-In-1
CAS No.	1426833-08-0
Molecular Formula	C₂₀H₂₀N₆O₂
Molecular Weight	376.41 g/mol
Synonyms	PDE2/PDE10-IN-1; PDE2/10 Inhibitor; 1426833-08-0; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(4-fluorophenyl)-6-methyl-N-(1-methyl-1H-pyrazol-5-yl)-; Dual PDE2/PDE10 Inhibitor; Research Compound 1426833-08-0; BML-341
EINECS	Contact for details

Quality Control

Every batch of Pde2/Pde10-In-1 is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for research use. Our standard quality commitment includes HPLC purity ≥98% and full spectroscopic characterization (NMR, MS). Certificates of Analysis (COA) with detailed chromatograms and spectra are supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under desiccant. The compound is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.