Description

3-Bromo-1-Methyl-1H-Indole-6-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate essential for advanced organic synthesis. Its core value lies in its dual reactive sites—the sulfonyl chloride and bromo groups—which enable precise, sequential functionalization for building complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of small molecule drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Employed to create activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex indole-based dyes and high-performance pigments.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-1-Methyl-1H-Indole-6-Sulfonyl Chloride
CAS No.	1423161-84-5
Molecular Formula	C9H7BrClNO2S
Molecular Weight	308.58 g/mol
Synonyms	6-(Chlorosulfonyl)-3-bromo-1-methyl-1H-indole; 1-Methyl-3-bromoindole-6-sulfonyl chloride; 3-Bromo-1-methylindole-6-sulfonyl chloride; 3-Bromo-1-methyl-1H-indole-6-sulfonchlorid; 3-Bromo-N-methylindole-6-sulfonyl chloride; Indole-6-sulfonyl chloride, 3-bromo-1-methyl-; 1423161-84-5
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-1-Methyl-1H-Indole-6-Sulfonyl Chloride is produced and tested under strict quality management systems. We guarantee high purity and consistency, with comprehensive analytical data provided for each lot. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are essential for your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.