Description

5-(Pentafluoroethyl)Pyridine-2-Carbonitrile is a high-value fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its unique structure, featuring a pentafluoroethyl group and a nitrile moiety, makes it an essential intermediate for creating compounds with tailored electronic and physicochemical properties. This product is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic systems to modulate bioavailability, metabolic stability, and receptor binding affinity.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and environmental stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands in coordination chemistry and catalysis, useful in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the creation of novel organic electronic materials, such as semiconductors or liquid crystals, where the electron-withdrawing pentafluoroethyl group fine-tunes electronic properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-(Pentafluoroethyl)Pyridine-2-Carbonitrile
CAS No.	1421951-81-6
Molecular Formula	C8H3F5N2
Molecular Weight	222.12 g/mol
Synonyms	2-Cyano-5-(pentafluoroethyl)pyridine; 5-(Pentafluoroethyl)-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 5-(pentafluoroethyl)-; Pentafluoroethylpyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-(Pentafluoroethyl)Pyridine-2-Carbonitrile is produced and controlled under a strict quality management system. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.