Description

Mutated Egfr-In-1 is a potent and selective small molecule inhibitor designed for targeted biological research. This compound is a critical tool for investigating signaling pathways associated with specific oncogenic mutations, offering high specificity and reliable performance in experimental settings. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in oncology, kinase biology, and drug discovery programs.

Application

• Biochemical Research: Used as a reference standard and active agent in in vitro assays to study the inhibition kinetics and potency against mutated EGFR targets.
• Drug Discovery & Development: Serves as a key pharmacological tool for high-throughput screening (HTS) and lead compound validation in oncology pipelines.
• Mechanistic Studies: Enables detailed investigation of downstream signaling cascades and resistance mechanisms in cellular models of non-small cell lung cancer (NSCLC) and other malignancies.
• Academic Research: Supports fundamental research in molecular biology and translational medicine, helping to elucidate the role of specific EGFR mutations in disease progression.
• Preclinical Development: Acts as a comparator compound in pharmacokinetic (PK) and pharmacodynamic (PD) studies during the preclinical evaluation of novel therapeutic candidates.

Basic Information

Product Name	Mutated Egfr-In-1
CAS No.	1421372-66-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Mutated EGFR Inhibitor-1; EGFR Mutant Inhibitor 1; EGFRm-In-1; 1421372-66-8; EGFR Mutation Inhibitor; Research Compound 1421372-66-8; Kinase Inhibitor for Mutated EGFR; Targeted EGFR Inhibitor
EINECS	Contact for details

Quality Control

Our Mutated Egfr-In-1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications and test results to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at -20°C under inert atmosphere. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.