Description

15(S)-Fluprostenol Isopropyl Ester is a synthetic prostaglandin analog, specifically an isopropyl ester derivative of fluprostenol. This compound is a critical high-purity reference standard and pharmaceutical intermediate used in advanced research and development. It is primarily required by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) working on ophthalmic solutions and other prostaglandin-based therapeutics.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the production of prostaglandin-based ophthalmic drugs for glaucoma treatment.
• Biochemical Research: Serves as a potent agonist for studying FP prostanoid receptor signaling pathways in vitro and in vivo.
• Veterinary Pharmaceutical Development: Investigated for applications in animal health, particularly in reproductive management.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for commercial-scale API synthesis.

Basic Information

Product Name	15(S)-Fluprostenol Isopropyl Ester
CAS No.	1420791-14-5
Molecular Formula	C₂₃H₃₁FO₅
Molecular Weight	406.49 g/mol
Synonyms	15(S)-Fluprostenol Isopropyl Ester; Fluprostenol Isopropyl Ester; 7-[(1R,2R,3R,5S)-2-[(1E,3S)-3-[(1R,2R)-3,3-Difluoro-2-hydroxy-1-(3-hydroxypropyl)cyclopentyl]prop-1-en-1-yl]-3,5-dihydroxycyclopentyl]hept-5-ynoic Acid Isopropyl Ester; Travoprost Isopropyl Ester Intermediate; Prostaglandin F2α Analog; FP Receptor Agonist
EINECS	Contact for details

Quality Control

Our 15(S)-Fluprostenol Isopropyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency for research and pharmaceutical applications. Quality is verified through comprehensive analytical testing including HPLC, GC, and NMR to confirm identity, purity, and isomeric composition. A detailed Certificate of Analysis (COA) is provided with each batch, documenting compliance with client specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
15(S)-Isomer Content	≥ 99.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.