Description

2-Amino-Benzenesulfonyl Chloride Hydrochloride is a key sulfonamide intermediate with high reactivity, essential for constructing complex molecular architectures. Its dual functional groups make it a versatile building block for introducing the sulfonamide moiety into target molecules, which is critical for modulating biological activity and physical properties. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty dyes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drugs, including diuretics, carbonic anhydrase inhibitors, and antibacterial agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides where the sulfonamide group enhances efficacy and selectivity.
• Dye and Pigment Manufacturing: Serves as a building block for creating azo dyes and other colorants with improved fastness and solubility properties.
• Material Science Research: Employed in the synthesis of monomers and polymers for advanced materials, such as sulfonated polymers for ion-exchange membranes.
• Chemical Biology & Proteomics: Utilized as a reagent for chemical proteomics and activity-based protein profiling (ABPP) to study enzyme function.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production in fine chemical CROs/CMOs.

Basic Information

Product Name	2-Amino-Benzenesulfonyl Chloride Hydrochloride
CAS No.	1417793-77-1
Molecular Formula	C6H7Cl2NO2S
Molecular Weight	228.10 g/mol
Synonyms	2-Aminobenzenesulfonyl Chloride Hydrochloride; o-Aminobenzenesulfonyl Chloride Hydrochloride; Benzenesulfonyl chloride, 2-amino-, hydrochloride; Anthranilic-2-sulfonyl Chloride Hydrochloride; 2-Sulfamoylbenzene Chloride Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-Benzenesulfonyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.