Description

n-Ethyl Azilsartan Medoxomil is a key pharmaceutical intermediate and a structural analog of the active pharmaceutical ingredient Azilsartan. This compound matters for its critical role in the research, development, and synthesis of next-generation angiotensin II receptor blockers (ARBs) used to treat hypertension. It is primarily needed by pharmaceutical R&D laboratories, API manufacturers, and fine chemical suppliers focused on cardiovascular drug development and process optimization.

Application

• Primary intermediate in the synthesis of Azilsartan and related antihypertensive API variants.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Key starting material (KSM) or advanced intermediate for process chemistry research and scale-up.
• Building block for medicinal chemistry programs targeting the angiotensin II receptor.
• Used in impurity profiling and stability studies of Azilsartan-based drug products.
• Critical material for the development of novel prodrug formulations.

Basic Information

Product Name	n-Ethyl Azilsartan Medoxomil
CAS No.	1417576-01-2
Molecular Formula	C₃₀H₂₆N₄O₈
Molecular Weight	570.55 g/mol
Synonyms	Azilsartan Medoxomil N-Ethyl Analog; (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-1-({4-[2-(5-ethyl-2H-1,2,3,4-tetrazol-2-yl)phenyl]phenyl}methyl)-1H-benzimidazole-7-carboxylate; TAK-536 Medoxomil Ethyl Ester; Ethyl Azilsartan Medoxomil; 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(5-ethyl-2H-tetrazol-2-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
EINECS	Contact for details

Quality Control

Our n-Ethyl Azilsartan Medoxomil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.