Description

1-Bromo-3-(trifluoromethoxy)-5-(trifluoromethyl)benzene is a high-value, multi-fluorinated aromatic building block of significant interest in advanced chemical synthesis. Its molecular structure, featuring both bromo and trifluoromethyl/trifluoromethoxy substituents, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Organic Synthesis & Catalysis: Acts as a versatile substrate in cross-coupling reactions (e.g., Suzuki, Negishi) and as a ligand precursor in organometallic chemistry.
• Material Science Research: Employed in the development of advanced polymers and coatings with specific chemical resistance and surface properties.

Basic Information

Item	Details
Product Name	1-Bromo-3-(trifluoromethoxy)-5-(trifluoromethyl)benzene
CAS No.	1417567-94-2
Molecular Formula	C8H3BrF6O
Molecular Weight	309.01 g/mol
Synonyms	3-Bromo-5-(trifluoromethoxy)benzotrifluoride; 5-Bromo-1-(trifluoromethoxy)-3-(trifluoromethyl)benzene; 1-Bromo-3-trifluoromethoxy-5-trifluoromethylbenzene; [1-Bromo-3-(trifluoromethoxy)-5-(trifluoromethyl)phenyl]; Benzene, 1-bromo-3-(trifluoromethoxy)-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-3-(trifluoromethoxy)-5-(trifluoromethyl)benzene adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO-aligned processes for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.