Description

3-(Trifluoromethyl)Pyridine-4-Carboxamide is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique trifluoromethyl-substituted pyridine core offers enhanced metabolic stability and lipophilicity, making it indispensable for developing advanced materials and bioactive compounds. This intermediate is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials requiring fluorinated aromatic units.
• Chemical Biology Probes: Utilized as a building block for designing molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	3-(Trifluoromethyl)Pyridine-4-Carboxamide
CAS No.	1416713-20-6
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	4-Pyridinecarboxamide, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)isonicotinamide; 3-Trifluoromethylpyridine-4-carboxylic acid amide; 3-CF3-Pyridine-4-carboxamide; 3-Trifluoromethyl-4-pyridinecarboxamide; 3-(Trifluoromethyl)-4-pyridinecarboxamide; 3-Trifluoromethyl-isonicotinamide
EINECS	Contact for details

Quality Control

Our production of 3-(Trifluoromethyl)Pyridine-4-Carboxamide adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.