Description

2-Bromo-3-Fluoropyridine-6-Carboxamide is a high-purity, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular modification is required. Its unique halogenated pyridine structure makes it an essential intermediate for medicinal chemistry, particularly in the synthesis of targeted kinase inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its halogenated pyridine core for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and complex organic frameworks in advanced material development.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	2-Bromo-3-Fluoropyridine-6-Carboxamide
CAS No.	1416712-39-4
Molecular Formula	C6H4BrFN2O
Molecular Weight	219.01 g/mol
Synonyms	6-Carbamoyl-2-bromo-3-fluoropyridine; 3-Fluoro-2-bromopyridine-6-carboxamide; 2-Bromo-3-fluoro-6-pyridinecarboxamide; 2-Bromo-3-fluoropyridine-6-carboxylic acid amide; 1416712-39-4; 6-Aminocarbonyl-2-bromo-3-fluoropyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoropyridine-6-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.