Description

2-Fuoro-5-Iodo-1,3-Dimethylbenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and iodine substituents on a dimethylbenzene core, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of advanced organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The iodine moiety is an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings, enabling rapid diversification of molecular scaffolds.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: The presence of a fluorine atom makes it valuable for studying structure-activity relationships (SAR) and metabolic stability in drug discovery.

Basic Information

Product Name	2-Fuoro-5-Iodo-1,3-Dimethylbenzene
CAS No.	1416549-07-9
Molecular Formula	C8H8FI
Molecular Weight	250.05 g/mol
Synonyms	1-Fluoro-2,4-dimethyl-5-iodobenzene; 5-Iodo-2-fluoro-1,3-dimethylbenzene; 2,4-Dimethyl-5-iodofluorobenzene; 2-Fluoro-5-iodo-m-xylene; 5-Iodo-2-fluoro-m-xylene; m-Xylene, 5-iodo-2-fluoro-; 1416549-07-9 (CAS); 2-Fluoro-5-iodo-1,3-dimethyl-benzene
EINECS	Contact for details

Quality Control

Our 2-Fuoro-5-Iodo-1,3-Dimethylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.