Description

2-Methyl-4-(Trifluoromethyl)Pyridine Hydrochloride is a high-purity, organofluorine building block essential for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of the trifluoromethyl group is critical for modulating biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethylpyridine moiety contributes to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorinated polymers, due to its unique electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	2-Methyl-4-(Trifluoromethyl)Pyridine Hydrochloride
CAS No.	1416354-37-4
Molecular Formula	C8H7ClF3N
Molecular Weight	209.60 g/mol
Synonyms	4-(Trifluoromethyl)-2-picoline hydrochloride; 2-Methyl-4-(trifluoromethyl)pyridine HCl; 2-Methyl-4-trifluoromethylpyridine hydrochloride; 2-Picoline, 4-(trifluoromethyl)-, hydrochloride; α-Methyl-4-(trifluoromethyl)pyridine hydrochloride; 4-(Trifluoromethyl)-2-methylpyridine hydrochloride; 2-Methyl-4-(trifluoromethyl)pyridinium chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(Trifluoromethyl)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.