Description

1-Bromo-2,5-Difluoro-3-Methylbenzene is a high-purity halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro and bromo groups impart specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Material Research: Employed in the development of novel polymers, ligands for catalysis, and specialty fine chemicals.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-Bromo-2,5-Difluoro-3-Methylbenzene
CAS No.	1416354-32-9
Molecular Formula	C7H5BrF2
Molecular Weight	207.02 g/mol
Synonyms	2,5-Difluoro-3-methylbromobenzene; 3-Bromo-2,6-difluorotoluene; 1-Bromo-2,5-difluoro-3-methyl-benzene; 2,6-Difluoro-3-bromotoluene; Benzene, 1-bromo-2,5-difluoro-3-methyl-; 3-Methyl-2,5-difluorobromobenzene
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2,5-Difluoro-3-Methylbenzene is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including GC, HPLC, and NMR, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.