Description

Cdk9 Inhibitor CAS NO 1415559-43-1 is a potent and selective small molecule inhibitor of Cyclin-dependent kinase 9 (CDK9), a key regulator of transcriptional elongation. This compound is a critical research tool for investigating cell cycle control, transcription, and apoptosis, particularly in the context of oncology and virology research. It is essential for pharmaceutical R&D, academic institutions, and biotechnology companies focused on developing novel therapeutics for cancers and other diseases driven by transcriptional dysregulation.

Application

• Biomedical Research: Fundamental studies on transcriptional regulation, cell cycle progression, and apoptotic pathways.
• Oncology Drug Discovery: A key pharmacological probe for validating CDK9 as a therapeutic target in various cancers, including hematological malignancies and solid tumors.
• Antiviral Research: Investigation of host-directed therapies for viral infections, as CDK9 activity is often co-opted by viruses like HIV for replication.
• Preclinical Development: Used in in vitro and in vivo models to assess the efficacy and mechanism of action of CDK9-targeting strategies.
• Chemical Biology: Serves as a reference compound for developing and screening new CDK9 inhibitors or profiling kinase selectivity panels.
• Signal Transduction Studies: Elucidation of the role of CDK9 in specific signaling cascades and disease models beyond cancer.

Basic Information

Product Name	Cdk9 Inhibitor
CAS No.	1415559-43-1
Molecular Formula	C₂₀H₂₀N₈O
Molecular Weight	388.42 g/mol
Synonyms	BAY-1251152; BAY 1251152; BAY1251152; (S)-N-(4-((4-((Dimethylamino)methyl)phenyl)amino)pyrimidin-2-yl)-6-methyl-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxamide; CDK9 Inhibitor (BAY-1251152); CDK9i; BAY1251152 (CDK9 Inhibitor); Atuveciclib
EINECS	Contact for details

Quality Control

Our Cdk9 Inhibitor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and potency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with our rigorous in-house specifications. For research requiring specific grade qualifications, please contact our technical support team.

Storage

Preserve in a tightly closed container,