Description

Btk Inhibitor 1 CAS NO 1412418-47-3 is a potent and selective small molecule inhibitor of Bruton's tyrosine kinase (BTK), a key enzyme in the B-cell receptor signaling pathway. This compound is a critical research tool for investigating B-cell malignancies, autoimmune disorders, and inflammatory diseases. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in drug discovery and preclinical studies.

Application

• Biochemical Research: Used as a reference standard and active pharmaceutical ingredient (API) in studies of BTK signaling pathways and its role in cellular proliferation and survival.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the synthesis and optimization of novel BTK-targeted therapeutics for oncology and immunology.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate the efficacy and mechanism of action of BTK inhibition.
• Pharmaceutical Intermediates: Acts as a high-value building block for the cGMP manufacturing of investigational new drugs (INDs).
• Cell Signaling & Pathway Analysis: A vital reagent for studying B-cell activation and related immune responses in research laboratories.

Basic Information

Product Name	Btk Inhibitor 1
CAS No.	1412418-47-3
Molecular Formula	C₂₅H₂₈N₆O₂
Molecular Weight	444.53 g/mol
Synonyms	BGB-3111; Zanubrutinib Impurity; (S)-7-(1-Acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,7-dihydro-5H-pyrazolo[4,3-d]pyrimidine-5-carboxamide; Bruton's Tyrosine Kinase Inhibitor 1; BTK Inhibitor; Btk1 Inhibitor; 1412418-47-3; Zanubrutinib Related Compound
EINECS	Contact for details

Quality Control

Our Btk Inhibitor 1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.