Description

Jnk Inhibitor CAS NO 1408064-71-0 is a potent and selective small molecule inhibitor targeting the c-Jun N-terminal kinase (JNK) signaling pathway. This compound is crucial for researchers and developers in the life sciences sector, as it enables precise modulation of cellular stress responses, apoptosis, and inflammation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for conditions such as neurodegenerative diseases, inflammatory disorders, and cancer.

Application

• Pharmaceutical Research & Development: A key tool compound for investigating the role of JNK signaling in disease pathology and validating JNK as a therapeutic target.
• Cell Biology Studies: Used in in vitro assays to study cellular stress responses, apoptosis (programmed cell death), and inflammatory pathways.
• Neuroscience Research: Applied in models of neurodegenerative diseases (e.g., Alzheimer's, Parkinson's) to understand and potentially mitigate neuronal cell death.
• Inflammation and Immunology: Employed to dissect the mechanisms of inflammatory diseases such as rheumatoid arthritis and to screen for anti-inflammatory agents.
• Oncology Research: Investigated for its potential to sensitize cancer cells to chemotherapy or to inhibit tumor growth and metastasis in preclinical models.
• High-Throughput Screening (HTS): Serves as a reference standard or positive control in drug discovery campaigns targeting kinase pathways.

Basic Information

Product Name	Jnk Inhibitor CAS NO 1408064-71-0
CAS No.	1408064-71-0
Molecular Formula	C₂₀H₂₀N₄O₂
Molecular Weight	348.40 g/mol
Synonyms	JNK Inhibitor; JNK-IN-8; (E)-3-(4-((3-(Pyridin-4-yl)-1H-pyrazol-1-yl)methyl)phenyl)-N-(quinolin-8-yl)acrylamide; 1408064-71-0; JNK Inhibitor VIII; JNK-IN-8 (JNK Inhibitor); c-Jun N-terminal Kinase Inhibitor
EINECS	Contact for details

Quality Control

Our Jnk Inhibitor is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all quality parameters. Our commitment to quality assurance supports reproducible and reliable results in your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.