Description

5-(Difluoromethyl)-2(1H)-Pyridinone is a high-purity fluorinated pyridinone derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a difluoromethyl-substituted heterocyclic moiety into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance biological activity and metabolic stability.
• Chemical Research & Development: Serves as a specialized reagent for introducing the difluoromethylpyridinone scaffold into complex organic molecules in academic and industrial R&D settings.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysis or components for electronic materials.

Basic Information

Product Name	5-(Difluoromethyl)-2(1H)-Pyridinone
CAS No.	1402550-75-7
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	5-(Difluoromethyl)-1H-pyridin-2-one; 2(1H)-Pyridinone, 5-(difluoromethyl)-; 5-(Difluoromethyl)-2-hydroxypyridine; 5-(Difluoromethyl)pyridin-2(1H)-one; 1402550-75-7
EINECS	Contact for details

Quality Control

Our 5-(Difluoromethyl)-2(1H)-Pyridinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.