Description

2-(3-Fluoropyridin-2-Yl)-2-Methylpropanoic Acid CAS NO 1402232-68-1 is a high-purity fluorinated pyridine derivative, a crucial building block in modern pharmaceutical and agrochemical research. Its value lies in its unique molecular structure, which incorporates both a fluoropyridine moiety and a carboxylic acid functional group, enabling precise chemical modifications. This compound is essential for medicinal chemists and process development scientists working on the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological systems and enzyme activity.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-(3-Fluoropyridin-2-Yl)-2-Methylpropanoic Acid
CAS No.	1402232-68-1
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	2-(3-Fluoropyridin-2-yl)-2-methylpropanoic acid; 2-Methyl-2-(3-fluoropyridin-2-yl)propanoic acid; 2-(3-Fluoro-2-pyridinyl)-2-methylpropanoic acid; α,α-Dimethyl-3-fluoro-2-pyridineacetic acid; 3-Fluoro-2-pyridineacetic acid, α,α-dimethyl-; 1402232-68-1; 2-(3-Fluoropyridin-2-Yl)-2-Methylpropionic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Fluoropyridin-2-Yl)-2-Methylpropanoic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ICH Q7 guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.